Sequential Analysis Using R for Monitoring Vaccines and Post-Marketed Drugs

Authors

  • Ivair R. Silva

Keywords:

Sequential analysis, Poisson Distribution, MaxSPRT, Power, Expected time of surveillance.

Abstract

This paper is dedicated to describe some of the main methods for sequential analyses devoted to post-market drug/vaccine safety surveillance. Considering the very practical problem of having adverse events arriving according to a Poisson stochastic process, here we present the use of the Sequential package for applications of the MaxSPRT method. The Sequential package was programed in the R language.

Published

10-02-2015

How to Cite

Silva, I. R. (2015). Sequential Analysis Using R for Monitoring Vaccines and Post-Marketed Drugs. Sigmae, 3(2), 68–87. Retrieved from https://publicacoes.unifal-mg.edu.br/revistas/index.php/sigmae/article/view/348