Adjustment of survival analysis model for tuberculosis data from the city of Patos de Minas - Minas Gerais

Authors

Keywords:

Parametric model, Covariates, Probability

Abstract

Tuberculosis has been one of the most studied their biological epidemiology, diagnosis, prophylactic and therapeutic aspects diseases. However this disease stubbornly persists worldwide, causing human suffering and death in the 21st century. Thus there is a need for epidemiological studies associated with statistical techniques such as Analysis of Survival have to study data from experiments in which the response variable is usually the time to occurrence of an event of interest being applied extensively in the medical field . In this paper the AFT parametric model was used to model the time until healing function of the covariates considered in determining the distribution that best fits the data , to analyze the effect of covariates on time to occurrence of an event , death from tuberculosis or healing in 437 patients detected with tuberculosis treated by the Regional Department of Health - Patos de Minas - MG , in the period 2003 - 2012. We conclude that in relation to the covariate sex, a female patient is 109.38 % more likely to cure that in masculine patients . The results also suggest patients from Patos de Minas city is 259.18 % more in the probability of cure than patients from other regions.

Author Biographies

Bruno Henrique Gomes, Universidade Federal de Uberlandia

Estudante de graduação em biotecnologia, lotado no Instituto de Genética e Bioquímica da Uiversidade Federal de Uberlândia.

Fabrícia de Matos Oliveira, Universidade Federal de Uberlandia

Graduação em Matemática pela Universidade Federal de Viçosa (2003), mestrado e doutorado em Estatística e Experimentação Agropecuária pela Universidade Federal de Lavras (2008 e 2012).  Atualmente é professora adjunta da Faculdade de Matématica da Universidade Federal de Uberlândia.

References

CHIRINOS, N. E. C.; MEIRELLES, B. H. S. Fatores Associados ao Abandono do Tratamento da Tuberculose: uma revisão integrativa. Texto & Contexto - Enfermagem, Florianopolis, v.

, n. 3, p.599-606, Jul. 2011. Disponvel em: http://www.scielo.br/pdf/tce/v20n3/23.pdf. Acesso em: 05 mar. 2014.

COLOSIMO, E. A.; GIOLO, S. R. Analise de sobrevivência aplicada. Sa~o Paulo: Edgard Blucher, 2006.

HIJJAR, M. A.; OLIVEIRA, M. J. P. R.; TEIXEIRA, G. , A tuberculose no Brasil e no mundo.Boletim de Pneumologia Sanitaria, Rio de Janeiro, v. 9, n. 2, p.9-16, dez. 2001.

MEDRONHO, R. A; BLOCH, K. V; LUIZ, R.R; WERNECK, G. Epidemiologia. São Paulo: Atheneu, 2006.

MINISTERIO DA SAUDE (MS), Manual de recomendações para o controle da tuberculose no Brasil. Brasília, 2011.

R CORE TEAM. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. 2012. ISBN 3-900051-07-0, URL http://www.R-project.org/.

SOUZA, M. V. N. A tuberculose e o desenvolvimento de novos tuberculostaticos em Far-Manguinhos (FIOCRUZ) no Rio de Janeiro. Revista Virtual de Qumica, Rio de Janeiro, v. 1, n. 1, p.9-16, fev, 2009. Disponvel em <http://www.u.br/RVQ/index.php/rvq/article/viewFile/11/1>. Acesso em: 03 mar. 2014.

WORLD HEALTH ORGANIZATION (WHO), Global Tuberculosis Report. Geneva, 2013. Disponvel em: http://www.who.int/tb/publications/global/report/en/. Acesso em: 03 mar. 2014.

WORLD HEALTH ORGANIZATION (WHO), Global Tuberculosis Report. Geneva, 2012. Disponvel em: http://www.who.int/tb/publications/global/report/en/. Acesso em: 28 jan. 2014.

Published

09-11-2015

How to Cite

Gomes, B. H., & Oliveira, F. de M. (2015). Adjustment of survival analysis model for tuberculosis data from the city of Patos de Minas - Minas Gerais. Sigmae, 2(3), 90–99. Retrieved from https://publicacoes.unifal-mg.edu.br/revistas/index.php/sigmae/article/view/234